The most common setting for finding anti-centromere antibodies is in patients with a limited cutaneous form of scleroderma. Anti-centromere abs are found in 22% of patients with systemic sclerosis and in 12% of patients with primary biliary cirrhosis, and are rarely present in normal individuals.
SST. Minimum volume 1 (0.5) mL serum. Stability: Ambient – 48 Hours, Refrigerated – 7 Days, Frozen – 2 Months